Follicular dysfunction induced by autoimmunity to zona pellucida.

بررسی تغییر شاخصهای قندی منطقه شفاف فولیکول در طی چرخه تخمدانی

 Glycoconjugates, particulary their sugar side chains, play important roles in development. This investigation was undertaken to examine the chemical nature of components in the zona pellucida possibly related to follicular development.           In this study, lectins conjugated to horseradish peroxidase were used as spec...

P-33: The Effect of Vitrification on Integrity ofZona Pellucida and Blastocyst Surveillance

Background: In spite of the great advances in vitrification, the mechanism of embryo damage which occure in some cases and varies from one case to another case is not exactly understood. Since Zona pellucida has an important role on early embryonic development, the aim of the present study is to investigate the effect of vitrification on integrity of zona pellucida and surveillance of blastocys...

Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx.

BACKGROUND Glycodelin-A interacts with spermatozoa before fertilization, but its role in modulating sperm functions is not known. Zona pellucida-induced acrosome reaction is crucial to fertilization and its dysfunction is a cause of male infertility. We hypothesized that glycodelin-A, a glycoprotein found in the female reproductive tract, potentiates human spermatozoa for zona pellucida-induced...

Title Zona pellucida-induced acrosome reaction in human spermatozoa is potentiated by glycodelin-A via down-regulation of extracellular signal-regulated kinases and up-regulation of zona pellucida-induced calcium influx

Assembly of the inner perivitelline layer, a homolog of the mammalian zona pellucida: an immunohistochemical and ultrastructural study.

The avian inner perivitelline layer (IPVL), a homologous structure to the mammalian zona pellucida, is deposited between the granulosa cells and the oocyte cell membrane during folliculogenesis. The glycoprotein meshwork of the IPVL forms a 3-dimensional matrix and possesses important functions in the fertilization process: it contributes to the binding of avian spermatozoa to the oocyte and in...